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Toxoplasmosis

Toxoplasmosis
May 21, 2021Articles49

Toxoplasmosis is a disease that results from infection with the Toxoplasma gondii parasite, one of the world’s most common parasites. Infection usually occurs by eating undercooked contaminated meat, exposure from infected cat feces, or mother to child transmission during pregnancy.It can also be transmitted through contaminated water.

Toxoplasmosis can be deadly or cause serious birth defects for a foetus if the mother becomes infected.
Most people who have toxoplasmosis never have any symptoms.The people who are most at risk for serious infections are those with compromised immune systems and infants born to mothers with active infection during their pregnancy.
Symptoms –


Most people who have been infected with the parasite that causes toxoplasmosis show no signs or symptoms.
People who develop symptoms may experience –
• Fever
• Headache
• Swollen lymph nodes, especially in the neck
• muscle aches
• Sore throat
Above mentioned symptoms can last for a month or more and usually resolve on their own.
People having weakened immune system could develop following symptoms-
• Brain inflammation, causing headaches, seizures, confusion and coma
• Lung infection, causing cough, fever and shortness of breath
• Eye infection, causing blurred vision and eye pain
When a fetus is infected, the symptoms may be mild or quite serious. Toxoplasmosis in an unborn baby can be life-threatening for the baby soon after birth.Most newborns with congenital toxoplasmosis may appear normal at birth but can develop sign and symptoms as they age.The baby is most at risk of contracting toxoplasmosis if you become infected in the third trimester and least at risk if you become infected during the first trimester. It is particularly important to check for involvement in their brain and eyes.
Many early infections end in stillbirth or miscarriage. Infants who survive are likely to be born with serious problems, such as –
• Seizures
• Jaundice
• An enlarged liver and spleen
• Severe eye infections
Only a small number of babies who have toxoplasmosis show signs of the disease at birth. Often, infants who are infected don’t develop signs- which may include hearing loss, mental disability or serious eye infections- until their teens or later.
Causes-


Toxoplasma gondii(T. gondii) is a single-celled parasitic organism that can infect most animals and birds. As because Toxoplasma gondii infectiousorganisms are excreted only in cat faeces, wild and domestic cats are theparasite’s ultimate host.
Although toxoplasmosis can’t be caught from an infected child or adult, you can become infected if you –
• Come in contact with cat faeces that contain the parasite
• Eat or drink contaminated food or water
• Use contaminated knives, cutting boards and utensils
• Eat unwashed fruits and vegetables
• Receive an infected organ transplant or transfused blood
When a person becomes infected with T. gondii, the parasite forms cysts that can affect almost any partof the body- often your brain and muscle  tissue of the different organs, including the heart.
Risk Factors –
You’re at risk of serious health problems from this infection if –
• You have HIV/AIDS
• You’re undergoing chemotherapy
• You take steroids or other immunosuppresent drugs
Complications-


The reason that pregnant woman should take special precautions to avoid toxoplasmosis is that it can be very serious, even fatal, for a baby infected in the uterus. For those who survive toxoplasmosis can have long lasting consequences on the –
• Brain
• Heart
• Eyes
• Lungs
They may also have mental and physical developmental delays and recurring seizures. Babies born with toxoplasmosis may have a higher riskof hearing and vision losses.
Diagnosis-
If you have the infection, your body will make things called antibodies to try to fight it off. To find out if you have toxoplasmosis, your doctor can do a blood test to see if you have those antibodies.
TORCH test for IgM and IgG antibodies gives confirmation of toxoplasmosis.
If you find out you have toxoplasmosis while you’re pregnant, you doctor will want to see it it has passed to your baby. They may recommend you –
• Ultrasound
• Aminocentensis
Treatment-
Toxoplasmosis  doesn’t cause problems for most people, so you probably won’t need treatment for it if your immune system is healthy.
If the patient is HIV positive or have AIDS, doctor may recommend the antibiotic sulfadiazine, along with pyrimethamine.
For a pregnant women whose baby hasn’t been affected, doctor might prescribe an antibiotic called spiramycin.
If the baby is also infected or is likely to be, the doctor may recommend sulfadiazine and pyrimethamine, but only after the 16th week of pregnancy. The doctor will watch the baby closely for signs of infection.
If your infant has toxoplasmosis or is likely to have it, treatment with pyrimethamine and sulfadiazine and folinic acid (leucovorin) is recommended.
Prevention–


Toxoplasmosis can be prevented by –
• Wear gloves when you garden or handle soil
• Don’t eat raw or undercooked meat
• Wash kitchen utensils, knives or cutting boards thoroughly after preparing raw meat
• Wash all fruits and vegetables properly
• Don’t drink unpasteurized milk
• Cover children’s sandboxes when they aren’t playing with that
Ayurvedic Perspective –
Toxoplasmosis can be correlated in Ayurveda under Putraghani Yonivyapad. The Ayurvedic treatment of toxoplasmosis is aimed at treating the symptoms, boosting the immune status of the body and preventing complications in immunocompromised and pregnant women.
Beneficial Herbs –
• Ashwagandha –


• Shatavari-


• Bala-


• Guduchi –


• Manjishta –


• Punarnava –


Effective Medications –
• Gandhak Rasayan
• Ras parpati
• Trivang Bhasm
• Triphla Gugglu
• Phala Ghrita
• Aarogyavardhini Vati
• Vasant Kusumakar Ras

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